Similar story here, but I'm thinking of going twice a week to be a little more evened out. I'm normally alright at the end of the week, but there have been some weeks where that very last day is rough.

Edited my post - sorry for not clarifying! 20mg EV. I'm taking 25mg Spironolactone in the morning and 50mg Spironolactone at night. I tried estradiol-only suppression and it didn't work out. I've always had a rough time with estrone conversion and androgen suppression. Was on 100mg Spironolactone once a day but developed pretty bad lightheadedness after about 3 years.

I do .15ml 20mg EV via IM once a week and it's great. My levels are even on the higher end. There are peaks and troughs but tbh it makes me feel more in touch with having an actual hormone cycle. Nothing crazy lol. For a couple days after the injection I'm hype and happy and then a couple days before I'm slightly more 🤷‍♀️ but everything else is normal. Couldn't imagine doing it more often than that.

My new Dr (who's much more progressive then my old clinic) just switched me over to weekly infections a little over a month ago. I currently take .38ml of 40mg/ml weekly and I've been feeling absolutely fabulous 🥰! I was on .5ml of mg/ml but that wasn't quite getting me where I wanted 😅 I  was only just over 200E and I wanted to go higher. I'm not sure what my new numbers are yet but I've definitely hit another growth cycle from the achs and pains 😂🤣 so I'm ecstatic lol

I was doing 0.25mL of 20mg/mL every 7 days (5mg/7 days). I was having really bad mood issues (I work direct care in a mental health facility so not really the best for my clients) and terrible hot flashes consistently on the last day of my shot cycle. I switched to 0.3mL every 6 days (6mg/6 days) so I’m still injecting once a week. We haven’t had my levels tested since starting EV injections but I feel SO MUCH BETTER just doing my shots every 6 instead of 7 days.

I do 5-day cycles if you want to try that. I don't feel like I'm always doing it

Switched from EC (5 mg/ml) to EV (40 mg/ml) recently due to the EC shortage. I was considering doing twice weekly, but opted for [EV once a week at .2 ml \(8 mg\)](https://sim.transfemscience.org/?e=ev&d=8&r=y&di=7&xm=90). I figured the minimum estradiol levels at that concentration are closer to the levels I had when I was taking [EC once a week at 1 ml \(5 mg\)](https://sim.transfemscience.org/?e=ec_o&d=5&r=y&di=7&xm=90). I suppose 9 or 10 mg would match closer to the minimum levels, though I decided not to since I was concerned about too high levels of estradiol.

I'm not on AA and there hasn't been any difference mentally nor physically after switching so it seems it's an appropriate dosage for myself.

Doing .25ml (5mg) from the 20mg/5ml EV every 5 days with 200mg progesterone at night no t blockers and levels are around 200e and 21t about to have my 60day blood test soon to see if it leveled off after starting it recently.

I'm doing pretty decent on EV 5mg (.12 mL 40mg/mL) IM 1x/wk. The last two days of the cycle can get a little weird but overall it's been good.

I'm on 0.6 EV every week (0.03 ml 20 mg/ml), monotherapy. Levels at mid point are fine. Levels at trough are a totally different question. I'm doing fine. I stay on that schedule for almost 2 years and I like it. No mood swings, headaches, fatigue, hot flashes. Sometimes I don't feel like injecting at all. I did an experiment and skipped 1 week. Still fine. 

I suspect things like this may be due to a small dose. Folks on higher doses may have quite different experience. I felt some of the reported effects when I was on a much higher dose.

I feel you, my Endo would prefer every 5 days for more even cycles/hormones, but I do every 6, it isnt as bad as 5 to me lol and better than waiting 7. I do have dips, but honestly theyre so minor for the past year or so I never noticed… until i started really checking for any changes and such.

Anyone here on Weekly EV doing well on that cycle?