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Just received this email:

“This is one of the harder emails we’ve had to write.

After a lot of thought and consideration, we’ve made the difficult decision to discontinue GetBit’s services.

Building GetBit has been a deeply personal journey for us. We started it because we genuinely believed in Bitcoin and wanted to make it easier for people in India to self-custody their Bitcoin. We’re incredibly grateful to everyone who trusted us with their money and chose to be part of that journey.

Unfortunately, over time, the viability of the business has become increasingly challenging, particularly due to the difficulties in accessing and operating through banking rails. After looking carefully

A new endoscopic procedure shows promise in helping people maintain weight loss after stopping GLP-1 medications. Interim trial results indicate that patients undergoing duodenal mucosal resurfacing regained significantly less weight compared to a control group. This minimally invasive treatment could offer a lasting solution for weight management, addressing a major unmet need for patients.

"As effective as GLP-1 medications are, many people stop taking them because of cost, side effects or simply not wanting to take a drug long-term," study leader Dr. Shelby Sullivan of the Dartmouth Geisel School of Medicine said in a statement"Finding a treatment that allows patients to stop these medic

A type of medicine called GLP-1 receptor agonists - more commonly known as weight-loss and blood sugar control drugs, such as Mounjaro (tirzepatide) and Ozempic (semaglutide) -are already widely used. These medicines may also help women with PCOS, who are more likely to experience obesity, insulin resistance, diabetes, and related heart and circulation problems.

Dr. Bakour said:

"The aim is to give women with PCOS evidence-informed, clearer treatment options and more consistent care. The project hopes to show whether these medicines can improve both general health and fertility health, while also helping local services develop clearer care pathways. Currently, care can vary, and women do n

April 20 (Reuters) - Indian drug regulators seized more than 260 suspected counterfeit pens of Eli Lilly's (LLY.N) obesity and diabetes drug Mounjaro ‌and said the main accused had ordered raw materials from vendors on Chinese e-commerce platform Alibaba.

Officials from the northern state of Haryana on Saturday recovered the suspected fake pens from a vehicle on the outskirts of New Delhi and arrested two people accused of making and selling the drugs, the Haryana Food and Drug Control Administration said in a ⁠statement.

The primary accused did not have a pharmaceutical licence and made the products at a private property, Drug Control Off

Reproductive symptoms, temperature-related complaints, and psychiatric symptoms were among the side effects of GLP-1 drugs reported in an analysis of Reddit posts.

“About 13% of users reporting side effects mentioned something in the psychiatric category, such as anxiety, insomnia, or depression.”

“Fatigue was the second most commonly reported symptom overall but has met relatively few reporting thresholds in existing trials,” he added. “This gap between what patients are self-reporting online and what gets captured in trials is really what motivated this whole line of work.

"Muscle health depends on sufficient protein intake and regular physical activity, especially resistance exercise. For people using GLP-1 RAs, reduced appetite can make it harder to meet protein needs, making what you eat matter more than ever, especially given that protein requirements tend to be higher in people with obesity and during active weight loss. Protein requirements should always be personalized, expressed as grams per kilogram of adjusted body weight, rather than treated as a one-size-fits-all target."

Read more: https://www.news-medical.net/news/20260409/Study-finds-nutritional-risks-in-users-of-GLP-1-drugs.aspx

- The FDA has approved a higher dose version of the injectable GLP-1 drug Wegovy (semaglutide) for weight loss.

- The new maximum dose is 7.2 milligrams per weekly injection, compared to the original maximum dose of 2.4 milligrams per week.

- A higher Wegovy dose could lead to greater weight loss, but it could come with side effects.

Higher dose Wegovy could lead to 25% more weight loss:

During the STEP UP phase 3b trial in 2025, the higher 7.2 mg dose of Wegovy gave an average weight loss of 18.7%. Around 1 in 3 participants saw at least a 25% weight loss.

The FDA stated that the higher dose of Wegovy was supported by clinical data showing a safety profile consistent with the known

Key Takeaways:

- A new diabetes study found that three years on a GLP-1 lowered the risk of heart attack, stroke, and early death by 82 percent.

- Interrupting or quitting GLP-1 therapy quickly reversed these benefits.

- Starting and stopping these drugs may put extra stress on the heart over the long run and make it harder to get the biggest improvement.

Excerpts:

Dr. Chen says it makes sense that these benefits would disappear if someone stops taking the medication, especially in the absence of dietary and lifestyle changes that support heart health.

Al-Aly says this reversal may be tied to weight regain, but there’s likely more to it than that. “We’re calling it a ‘metabolic re

- Alkem rolls out 80% cheaper variant of semaglutide in India- https://pharma.economictimes.indiatimes.com/news/drug-approvals-and-launches/alkem-rolls-out-80-cheaper-variant-of-semaglutide-in-india/129715108

- Sun Pharma joins semaglutide race with over 60% cheaper generic: Noveltreat (for weight-loss) will cost patients between Rs 3,490 and Rs 7,400 while Sematrinity (for type-2 diabetes) monthly cost ranges between Rs 2,960 and Rs 4,790. - [https://pharma.economictimes.indiatimes.com/news/drug-approvals-and-launches/sun-pharma-joins-semag

Beginner's complete guide - https://www.reddit.com/r/

GLP1India/s/1ХsgeAi4iB

Videos on how to use a MJ Kwikpen - https:// www.reddit.com/r/GLP1India/s/ZSs7Mx5wfx

Mounjaro Kwikpen split dosing calculations - https:// www.reddit.com/r/GLP1India/s/PHiDP7HkzA

Other tidbits/ hacks - https://www.reddit.com/r/GLP1India/ s/LjMTaWju3w

Beware of scammers in your DMs and comments, here's how to report suspicious content - https:// www.reddit.com/r/GLP1India/s/6wpuEywygA

https://pharma.economictimes.indiatimes.com/news/pharma-industry/zydus-set-for-day-1-launch-of-semaglutide-generic-with-reusable-multi-dose-pen/128799190