Propylhexedrine HCl synthesis from scratch idea.
You can get Cyclohexyl Bromide and react it with Acetone Enolate formed from Dry Acetone in Sodium Ethoxide in refluxing Ethanol using dry 99% Ethanol and Sodium Metal. Then it forms Cyclohexyl-2-Propanone and a little bit of 1,3-Dicyclohexyl-2-Propanone impurity. Then, react Acetamide with Sodium Hypochlorite and Sodium Hydroxide to get Methylamine. Then, condense Cyclohexyl-2-Propanone and Methylamine in 95% Ethanol to get Cyclohexyl-2-Propanone Methylimine and you can add Formic Acid to bring the pH to 4.5 for imine formation of Cyclohexyl-2-Propanone=NHCH3 or Cyclohexyl-2-Propanone Methylimine. Then, add Dry Ice pellets to create a Carbon Dioxide inert atmosphere. Have a fire extinguisher just in case things go wrong. Add Aluminum Palladium Galinstan amalgam (300g Aluminum + 100g Galinstan + 50mg Palladium) Galinstan amalgam (300g Aluminum + 100g Galinstan) and 500mg of Palladium on Carbon catalyst and Iron Powder to help it work better in the wet environment of the reaction flask and Formic Acid and keep the pH around 4.5. Then, heat it to 30°C and keep it there for 24 hours and make sure you keep the Carbon Dioxide inert atmosphere. You will get a grey solution of Propylhexedrine freebase in Ethanol Water and Al(OH)3 grey water and Palladium Galinstan (50mg Palladium and 100g of Galinstan, you can dry the amalgam and add 300g of Aluminum Foil in a crucible for Aluminum Palladium Galinstan amalgam) and Iron Powder at the bottom. Filter it through a Buchner Funnel with filter paper and Zeolite add more 95% Ethanol to the flask and filter it through a Buchner Funnel with filter paper and Zeolite. You have clear Propylhexedrine freebase in Ethanol Water. Then, dry it with Anhydrous Magnesium Sulfate and Filter it through a Buchner Funnel with filter paper. Then you have Propylhexedrine oil in dry Ethanol. Bubble HCl through it to get Propylhexedrine HCl.
Posted Jul 12, 2025, 4:06 PM UTC