Medical background and timeline

From October until June I used isotretinoin (Accutane). At the end of August I developed a STEC bacterial infection. Since then, I have been struggling with persistent and severe histamine ishu that have not resolved for months. (While taking Accutane, I did start to experience occasional symptoms of elevated histamine levels.)

Based on a test, I have a leaky gut, . . My zonuline 75! Normaly is under 50

Main symptoms •	Strong histamine reactions about 20 minutes after eating •	Severe bloating that increases during the day (flat stomach in the morning) •	Constipation •	Gas and abdominal distension after eating fiber-rich foods such as broccoli, carrots, and sweet potatoes •	Nausea after eating rice and potatoes • stool is more yellow •low libido

The histamine reactions are currently the most debilitating symptom and significantly affect my quality of life.

Microbiome findings

Several abnormalities stand out in my microbiome analysis: •	Strongly elevated fiber-degrading bacteria, especially : Bifidobacterium adolescentis •	Strongly elevated lactate-producing bacteria, including Bifidobacterium spp. •	Mildly elevated methane-producing archaea, such as Methanobacteria and Methanobrevibacter spp.

Mildly elevated: Escherichia spp.** Nobody can give me a solution… pfff. I live in belguim

I really need help.. I don't know what I can do

Sibo test negative.. but i think I have Sibo. Leaky gut, verry bad histamine intolerance, constipation…