r/floxies•
Meowpol

Ongoing reactive foot pain post levofloxacin

[TREATMENTS]

I’m honestly at my wits end with all of this. I’m a 30 year old female, previously very healthy and able to engage in regular exercise. In early May of this year, I took 4x doses of levofloxacin for a resistant H pylori infection. I couldn’t complete the full course due to bad pain in my legs and feet. Since then, the pain has become mainly localised to my feet (sometimes with hand involvement, but no way near as bad as my feet). The symptoms include constant vibrating of the feet, spasming, sometimes burning/pins and needles, and every time I exercise (including after longer walks) I get massive painful flare ups which result in sharp cramping pain and toe spasms in my feet. These symptoms have significantly affected my quality of life, and the pain frequently reduces my quality and duration of sleep. I went from moderate to high intensity exercise 3-4x week, to being almost completely sedentary to avoid flare ups. I’ve seen multiple GPs, a neurologist and a podiatrist who all do not know what is causing the symptoms, even though I tell them the symptoms started during levofloxacin treatment - they aren’t able to prove that it’s due to the antibiotic. MRIs have ruled out multiple sclerosis and an ultrasound ruled out chronic neuritis/compartmental peripheral neuropathy. I am still awaiting completion of a nerve conduction study. I just don’t know where to go from here. If anyone has any suggestions (including supplements that would potentially help, or recommendations for doctors to see), that would be greatly appreciated.

Note: I am currently taking turmeric, fish oil, magnesium and vit C supplements. I’ve also tried NAC and glutathione with no benefit.

Posted Sep 12, 2025, 11:35 PM UTC

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