At what point in a flare do you decide your current meds aren’t working?

Hi, I’m new to UC (diagnosed ~1 year ago, symptoms getting slightly worse over time but largely I’m used to it). About a month ago I started flaring and now I’m severely anemic, going every 4 hours even through the night. At what point do you call it quits and ask for prednisone? Is there a protocol somewhere I can see when meds are switched out and what the next med is?

I’m maxed out on mesalamine (orally and rectally). Also just started taking soluble fiber which actually seems to be working quite well in forming up my stools.

Unfortunately my doc is a bit booked out so my next appointment with him isn’t for another few months :(