Is it safe to synchronize home with non-nixos distro ?

I want to try Nix OS with home-manager on my new laptop. I have my current laptop with MX linux and it just works. I want to use rsync to keep the two homes in sync. I try to keep it simple. The home-manager will not contain any setting that can be done through dotfiles, I just want to install packages without sudo. Is home manager will break my config files made with MX ?