Car makes rubbing metallic sound at 40 mph or higher, sound isn’t consistent. Can’t pin point the sound but I have a suspicion that it’s the dust cover and rotor. Sound happens around 0:09 and vehicle is a Lexus IS350 2008

I can't hear anything unusual in the clip but if there is a metallic rattling noise at certain speeds or RPMs, the cause is usually a heat shield.

When was the last time your tires were balanced? Your tires being off balance can also cause weird noises that only happen at certain speeds. This can happen if a wheel balancing weight falls off, which happens all the time.