Source
r/Warframe•
firstsymph

What weapons did you all use to kill Sisters?

Question/Request

I'm having quite a hard time to deal with sister's bs damage reduction. Not only it takes eons to take out just the shield but also it took sister to one shot me in 10 seconds while I desperately trying to deal damage to a rank 4/5. I need help with making this grind enjoyable. So far base on my painful experience the weapons I have a bit better time are:

  • Primary: Ignis Wraith- mainly use it to take out shield. I tried it with Kuva Khom. The result was slower and damage wasn't any better.

  • Secondary: Aksomati Prime/Kuva Nukor- use it after shield is taken out. It feels like weapons with innate slash do just a bit better. (just a little)

  • Melee: I really struggle in this one. My better experience is with Nikana Prime (non-heavy build) spam E for god knows how long. My Tatsu heavy attack build which has been my main boss killer for so long is no longer effective, and in fact it hits as hard as about the same as a single E normal would do. My Venka Prime which I use to shred Deimos mobs with also performs worse than Nikana for some reason even though it's modded the same way.

Posted Jul 12, 2021, 11:30 PM UTC

634
cuyeritossLoki Master Race•

Banshee + any weapon, really.

13
Ravenmausi•

Jupp. Banshee is the Dominatrix of the Nemesis

5
Grunslik•

Cedo or Mesa's Peacemaker using an element the Sister is weak against.

8
BuffMarshmallow•

First of all, Cedo with a semi-specific build to not reach a burst damage threshold.

Second, any naturally good fire rate secondary with a weird build that does jack shit damage to anything but sisters because it abuses their DPS calculation thresholds.

7
BlackGShiftMR 30 and never uses Inaros •

Can you explain more about the Cedo build

5
BuffMarshmallow•

I'll just link you to the original post with it where I got the idea from Here

5
CrazyEvilwarboss•

Ignis Wraith magnetic and done .... didn't bother much because 3 other dude will help to kill it fast

3
Leekshooter•

Seer

Might really push the boat out and try stug again, since I still have that riven

3
Kamikae_Varluk•

Valkyr prime with duration and umbra mods, Kuva Bramma with crit stat riven, Kuva Nukor with high status, red crit dokram with seekhalla and vargeet II jai pretty generic crit melee build, panzer Vulpaphyla, no necramech for final fight. With the above I’ve had no issues with even a level 5 sister. Honestly I just Nukor the shield down and pop hysteria and claw them to death.

2
RealAstropulse•

Anything well modded does the trick tbh. Although the staltha is pretty good specifically. (Alt fire)

2
LuminareTaco•

Use banshee's 2 and then it's dead. Even your pet can kill it.

2
Ok-Ad3443•

loki and kuva zarr in the face

2
anon-03057271894•

My way works but it’s expensive, I’m sure there’s a better way.

Bramma or Supra Vandal + Magnetize and Breach Surge. Use Unairu Void Dash and you can yeet off all the armor when you need to recharge from the sister one-shotting your shields.

1
asillynert•

Alt fire new detron or even semi auto old ones but one alt fire anything rank 3 or under is downed. Then been rolling either mag and bubble or banshee and can drop even higher just as easily

Other pre sister weapons twin khomak is really only non detron pistol not alot of good stuff out there.As for primarys cedos does a bit of double dipping right builds its outright ridiculous innate condition overload with new status condition overload PLUS extra multishot it melts sisters.

Really any shot gun on mag will do alright and if you get banshee multiplier nyx armor strip etc really any do decent. Didn't test on sisters but was doing endurance arcane steel path run. And fully stack whip on acolyte was 2-3 hitting him. And in terms of tankiness acolytes have felt about rank 3 sister minus annoying port/shield gate crap.

1
Ironbatman300•

I recommend high crit, low status, both sisters and liches have a limit on the number of stacks of status effects, 4 per status type

1
MrJereMeeseeks•

No onto the low status side. The healthbars melt with my rattleguts when its proccing radiation/viral/slash and tickles the sister if it's only crits without status procs. Status effects cap out at 4, sure, but that's not why we are modding for an elemental combo.

1
Present-Court2388•

MESA or mirage with gram prime and kuva zarr shotgun

1
jDubKing•

one of the new tenet or new kuva weapons. i use whatever i am leveling and use banshee

1
[deleted]•

I shield strip with Nyx then use Cedo with primed point blank removed. The lack of base damage lowers the DR threshold and Cedo's CO passive can hit harder.

1
luigislam•

Nekros' Shadows and my Sentinel rocking out a pimped out and Deth Machine Rifle with Riven. Slapped in Theorem Infection too. Obviously not that highly effective and its a pricy build setup but hey it works and I enjoy it lol

1
pf2-•

That title lol

1
deathshdw99•

Xaku with Cedo. Perma cc with 3rd ability and just stand in front of her with your 2 acrive. Shoot her with Cedo's alt fire then primary at intervals to bypass the DR scaling. Profit.

1
MidnightCoru•

I have been using a mausolon. Scales fairly well so long as you get enough headshots

1
JINXnocturnalLegendary ■ PS4•

I use a high strength, low duration Trinity with Pillage, Kuva Zarr (electric) and Kuva Twin Stubba (electric and Magnetic). EV can be cast on Sisters, and at the strength I have her, deals 60% true damage. Eats large chucks of health.

1