I always play in English with no subtitles. Since I doubt there's a way to have subtitles turn on specifically for Spanish lines, I imagine I'll have to deal with missing part of the dialogue. Just in the beginning, that happened with the cops. It'll be just like real life I guess.
My question is whether or not I'll miss out on major lines related to the plot. Something like a two minute scene in a different language?
I don't know if subtitles are heavily recommended for this game or not....
